35. The correct answer is B. The tumor is hepatocellular carcinoma, which usually develops in the setting of cirrhosis owing to a variety of damaging agents, including hepatitis B virus (HBV) infection, alcohol use, and hemachromatosis.
Epstein-Barr virus (EBV; choice A) is associated with Burkitt lymphoma and nasopharyngeal carcinoma.
Human herpesvirus type 8 (HHV 8; choice C), a member of the herpes family, is associated with Kaposi sarcoma.
Human papillomavirus (HPV; choice D) is associated with cervical, penile, and anal carcinoma.
Human T-lymphocyte virus (HTLV-1; choice E) is associated with adult T-cell leukemia.